Amino Acids
Posted by admin | Under Health Supplements Saturday Nov 14, 2009
How can changing the sequence of amino acids in the primary structure of a protein influence the tertiary and?
How can changing the sequence of amino acids in the primary structure of a protein influence the tertiary and even quaternary structures of proteins?
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The chemical properties of their unique amino acid sequence cause polypeptides to fold into a precise shape. The total folded shape of one polypeptide is protein tertiary structure. Many polypeptides are functional proteins after they have folded into their unique tertiary structure. Each protein is a precision machine. Like a robot, it can do only one thing over and over. Therefore it must have a precise structure. The protein folds in a watery environment. The interactions of the protein’s sidechains with water influence the way the protein folds.
Each R-group or sidechain of the 20 types of amino acids has a unique chemical structure. These sidechains have chemical properties that influence protein folding
If the amino acid sequence was to be altered, protein folding does not occur properly and thus leads to loss of its function.
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